Special groups special needs?

Massimo Puoti – Dept of Infectious Diseases – Niguarda Hospital – Milan, Italia


Hepatitis C Virus (HCV) causes extrahepatic disorders: cryoglobulinemia, lymphoproliferative
disorders, kidney and autoimmune inflammatory diseases. These conditions even
id subclinical should be identified in patients with HCV infection and screening for HCV
should be included in the clinical workup of these dsorders Early treatment of HCV infection
may halt the evolution of some of these disorders. The availability of Interferon
free all oral antiviral treatments has completely changed the clinical scenario of these
condition and the first reports confirm the efficacy of this approach even in patients with
extrahepatic disorders. Nevertheless a point of no return exists for all of them when HCV
eradication is not sufficient to reverse the clinical course of the disease. In this case other
approach should be combined or follow antiviral therapy in HCV infected subjects.
Parole chiave: HCV; Cryoglobulinema: lymphoma; Renal insufficiency

Articolo presente in – Cure and Chronicity N.1 

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